LAINE, DAVID JOSE SIMON,POLLARD, MATTHEW,DOYLE, ANTHONY GERARD,POULTON, LYNN DOROTHY,CLARKE, ADAM WILLIAM
申请号:
CA3046387
公开号:
CA3046387A1
申请日:
2017.12.21
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Recombinant antibodies that specifically bind to IL-15 as well as a complex of IL-15 and the IL-15 Receptor-alpha are provided. The antibodies inhibit immune cell proliferation, and are capable of use in the treatment of any autoimmune or inflammatory disease or condition where IL-15 is dysregulated, including Celiac disease.