David Jose Simon LAINE,Matthew POLLARD,Anthony Gerard DOYLE,Lynn Dorothy POULTON,Adam William CLARKE
申请号:
US16471616
公开号:
US20200270339A1
申请日:
2017.12.21
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Recombinant antibodies that specifically bind to IL-15 as well as a complex of IL-15 and the IL-15 Receptor-alpha are provided. The antibodies inhibit immune cell proliferation, and are capable of use in the treatment of any autoimmune or inflammatory disease or condition where IL-15 is dysregulated, including Celiac disease.