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PRODRUG OF AN ICE INHIBITOR
- 专利权人:
- VERTEX PHARMACEUTICALS INCORPORATED
- 发明人:
- Marion W. WANNAMAKER,Robert J. DAVIES
- 申请号：
- US15974855
- 公开号：
- US20180327449A1
- 申请日:
- 2018.05.09
- 申请国别(地区):
- US
- 年份:
- 2018
- 代理人:
- 摘要：
- This invention describes an ICE inhibitor prodrug (I) having good bioavailability.Compound I is useful for treating IL-1 mediated diseases such as rheumatoid arthritis, inflammatory bowel disease, Crohn's disease, ulcerative colitis, inflammatory peritonitis, septic shock, pancreatitis, traumatic brain injury, organ transplant rejection, osteoarthritis, asthma, psoriasis, Alzheimer's disease, myocardial infarction, congestive heart failure, Huntington's disease, atherosclerosis, atopic dermatitis, leukemias and related disorders, myelodysplastic syndrome, uveitis or multiple myeloma.
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
