МАКДОНАЛД Линн (US),МАКУИРТЕР Джон (US),ГЮРЕР Каган (US),ХОСИАВА Каролина А. (US),МЕРФИ Эндрю Джей (US)
申请号:
RU2016139418
公开号:
RU2016139418A
申请日:
2012.10.17
申请国别(地区):
RU
年份:
2018
代理人:
摘要:
Allow mouse provided by a restricted heavy chain immunoglobulin field, wherein feature of place is the D H gene segments and multiple J H gene segments of the V H gene segments of a single polycrystalline people, multiple people. Method for manufacture antibody sequence that combine an antigen (such as. One viral antigen) it provides, including exempting a mouse with interested antigen, wherein mouse includes the D H gene segments and multiple J H gene segments of the V H gene segments of a single people, multiple people, in interior endogenous immunoglobulin heavy chain place.