compound, method of inhibiting pak1 activity, method for treatment, process, composition, use of a compound and invention
- 专利权人:
- F. HOFFMANN - LA ROCHE AG
- 发明人:
- IGNACIO ALIAGAS-MARTIN,JAMES JOHN CRAWFORD,JOACHIM RUDOLPH,SIMON MATHIEU,WENDY LEE
- 申请号：
- BR112014015549
- 公开号：
- BR112014015549A2
- 申请日:
- 2012.12.21
- 申请国别(地区):
- BR
- 年份:
- 2017
- 代理人:
- 摘要：
- Compounds having the formula I wherein A, R1a, R1b, R2, R3, R4, R5, R6, R7, R8, Ra, Rb, X1, X2, X3 and n are as defined herein are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.
- 来源网站：
- 中国工程科技知识中心
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