4-trimethylammonium butyrate compounds, process for their preparation, pharmaceutical compositions comprising them, method for the therapeutic or prophylactic treatment of diseases that are modulated by cpt2 inhibitors and uses of the compounds
MIRJANA ANDJELKOVIC,ODILE CHOMIENNE,PATRIZIO MATTEI,SIMONA M. CECCARELLI
申请号：
BRPI0910591
公开号：
BRPI0910591A2
申请日:
2009.04.20
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
This invention relates to novel 4-trimethylammoniobutyrates of the formula wherein A1, R1, m and n are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds inhibit carnitine palmitoyl transferase (CPT) activity, in particular CPT2 activity, and can be used as medicaments.
