EFFECTIVENESS OF ANTIBODY ANTIBODIES AGAINST TROP-2 WITH MEDICINE SN-38 FOR THERAPY OF REDUCING / REFRACTIVE TO TUMOR CONTROL POINT INHIBITORS

• 收藏
• 分享

专利权人:

发明人:

申请号：

RU2018139610

公开号：

RU2018139610A3

申请日:

申请国别(地区):

RU

年份:

2020

代理人:

摘要：

The present invention relates to therapeutic ADCs comprising SN-38 attached to an anti-Trop-2 antibody or antigen-binding antibody fragment, more particularly sacituzumab govitecan. The ADC is administered to a subject with a Trop-2 positive cancer that is resistant to or relapsed from prior treatment with a checkpoint inhibitor. The therapy is effective to treat cancers that are resistant to checkpoint inhibitors.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/