The present invention is directed to a relates systemic immunity and gut immunity reinforcing agents including KiyoshiKojihishio ethanol dissolved extract as an active ingredient, immunopotentiator (adjuvant) comprising an Kiyoshi Kojihishio ethanol dissolved extract of the present invention, safety is ensured By using the food material is, no toxicity and side effects, it is possible to provide the inexpensive production costs and the use of convenience. Moreover, immunization reinforcing agents of the present invention, when the immunogen and oral, oral infectious pathogenic microorganisms, as well as parenteral infectious pathogenic microorganisms or viruses, a cancer antigen, such as against common antigens, Th1 and Th2 The reaction was induced, and it is possible to produce an effective specific antibodies (IgG in blood and intestinal IgA). .BACKGROUND 10本発明は、清麹醤エタノール溶解抽出物を有効成分として含む全身免疫及び腸管免疫補強剤に関するものであって、本発明の清麹醤エタノール溶解抽出物を含む免疫補強剤は、安全性が確保された食品素材を使うことによって、毒性及び副作用がなく、安価の生産コストと使用の便宜性とを提供することができる。また、本発明の免疫補強剤は、免疫原と経口投与時、経口感染性病原性微生物はもとより、非経口感染性病原性微生物やウイルス、癌抗原、一般抗原などに対しても、Th1及びTh2反応を誘導し、効果的な特異抗体(血中IgG及び小腸IgA)を生産することができる。【選択図】図10
