PROBLEM TO BE SOLVED: To provide an inhibitor of production of advanced glycation end product comprising substances capable of inhibiting production of advanced glycation end product that is thought to be a causative substance of various lifestyle diseases, useful for prevention and/or treatment of lifestyle disease, particularly diabetes or diabetic complications, and having few adverse effects.SOLUTION: Provided is an inhibitor of production of advanced glycation end product comprising a Persicaria hydropiper (Polygonum hydropiper) f. purpurascens extract and/or a Persicaria hydropiper (Polygonum hydropiper) var. laetevirens extract as active ingredients.COPYRIGHT: (C)2014,JPO&INPIT【課題】種々の生活習慣病の要因物質と考えられている終末糖化産物の生成を抑制することができる物質を含み、生活習慣病、特に糖尿病もしくは糖尿病合併症の予防および/または治療に有用であり且つ副作用の少ない終末糖化産物生成抑制剤を提供すること。【解決手段】ムラサキタデ抽出物および/またはアオタデ抽出物を有効成分として含有する終末糖化産物生成抑制剤を提供する。【選択図】なし