Ronnie Tung Ping Poon;Sheung Tat Fan;David S. F. Young;Terence Kin Wah Lee;Daad Sayegh
发明人:
David S. F. Young,Daad Sayegh,Sheung Tat Fan,Ronnie Tung Ping Poon,Terence Kin Wah Lee
申请号:
US13243870
公开号:
US08388961B2
申请日:
2011.09.23
申请国别(地区):
US
年份:
2013
代理人:
摘要:
This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of primary and metastatic human tumor cells; and most particularly to the use of an isolated monoclonal antibody or cancerous disease modifying antibodies (CDMAB) thereof, optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response in such human tumors, e.g. any primary or metastatic tumor sites which arise from hepatocytes. The invention further relates to binding assays which utilize the CDMAB of the instant invention.