Nicholas McGranahan,Rachel Rosenthal,Charles Swanton,Karl Peggs,Sergio Quezada
申请号：
US16565350
公开号：
US20200000904A1
申请日:
2019.09.09
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to a method for identifying a truncal neo-antigen in a tumour from a subject which comprises the steps of: i) determining mutations present in a sample isolated from the tumour； and ii) identifying a truncal mutation which is a mutation present in essentially all tumour cells； and iii) identifying a truncal neo-antigen, which is an antigen encoded by a sequence which comprises the truncal mutation.
