INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)
发明人:
FRANCINE BEHAR-COHEN
申请号:
PT11740931
公开号:
PT2603238E
申请日:
2011.08.08
申请国别(地区):
PT
年份:
2014
代理人:
摘要:
A method of treating an ocular disease in a subject includes delivering a pharmaceutical composition into a ciliary muscle of the subject and inducing transfection of the therapeutic nucleic acid into the ciliary muscle by exposing the pharmaceutical composition to ultrasound. The pharmaceutical composition comprises echo-contrast agent microbubbles and a therapeutic nucleic acid.