The invention includes a method for combating scarring in a subject, the method comprising administering to the subject an agent which positively modulates β2-adrenergic receptor； a method for simultaneously decreasing the amount of TGFβ1 and increasing the amount of TGFβ3 produced by a fibroblast, the method comprising contacting the fibroblast with an agent which positively modulates β2-adrenergic receptor； a method for reducing fibroblast differentiation, the method comprising contacting the fibroblast with an agent which positively modulates β2-adrenergic receptor； and a method of reducing the deposition of collagen in a subject, the method comprising administering to the subject an agent which positively modulates β2-adrenergic receptor.
