Disclosed herein are kits and methods for treating appetite suppressing disorders and disorders with an increased metabolic rate by neuromodulation. A method of treating an appetite suppressing disorder or a disorder with an increased metabolic rate in a patient may include identifying the brain structure that is subject to modulation in the patient and modulating the activity of one or more brain structures by applying electrical stimulation to one or more brain structures of a patient. A kit may include: a neuromodulation device and instructions for using the neuromodulation device to modulate activity of a brain structure by applying electrical stimulation to one or more brain structures of a patient for treatment of an appetite suppressing disorder or a disorder with an increased metabolic rate.