Biogen International Neuroscience GmbH;University of Zurich
发明人:
Weihofen, Andreas,Grimm, Jan,Hock, Christoph,Nitsch, Roger,Su, Lihe,Weinreb, Paul
申请号:
AU2012272790
公开号:
AU2012272790B2
申请日:
2012.06.22
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
Provided are anti-human α-synuclein-specific binding molecules, e.g., antibodies or antiben-binding fragments, variants or derivatives thereof, as methods related thereto. Further provided are anti-human α-synuclein binding molecules which bind to specific N-terminal and C-terminal epitopes on human α-synuclein. The binding molecules described herein can be used in pharmaceutical and diagnostic compositions for α-synuclein targeted immunotherapy and diagnosis, respectively.