Biogen International Neuroscience GmbH;University of Zürich
发明人:
Andreas Weihofen,Jan Grimm,Christoph Hock,Roger Nitsch,Lihe Su,Paul Weinreb
申请号:
US15410128
公开号:
US09975947B2
申请日:
2017.01.19
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided are anti-human α-synuclein-specific binding molecules, e.g., antibodies or antiben-binding fragments, variants or derivatives thereof, as methods related thereto. Further provided are anti-human α-synuclein binding molecules which bind to specific N-terminal and C-terminal epitopes on human α-synuclein. The binding molecules described herein can be used in pharmaceutical and diagnostic compositions for α-synuclein targeted immunotherapy and diagnosis, respectively.