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DNA APTAMER BINDING TO NON-SMALL CELL LUNG CANCER CELLS (H1975)
专利权人:
NISSAN CHEMICAL INDUSTRIES; LTD.
发明人:
Hitoshi FURUSHO
申请号:
US15549843
公开号:
US20180016582A1
申请日:
2016.02.05
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The objective of the present invention is to provide a novel DNA aptamer useful for the diagnosis, treatment, and prevention of metastasis, and the like, of lung cancer.A DNA aptamer comprising specifically binding to a non-small cell lung cancer cell, in which the DNA aptamer has at least one nucleotide sequence selected from the sequence of SEQ ID NOs: 1 and 2; a composition for detecting lung cancer cell, comprising the DNA aptamer; a kit for detecting lung cancer cell, comprising the DNA aptamer; a method for detecting lung cancer comprising using the DNA aptamer; a detection method comprising contacting the DNA aptamer with a sample obtained from the living body selected from the group consisting of lung cells, lung tissues, blood, serum, plasma, saliva, and sputum and detecting the presence of a lung cancer cell by observing the response caused by the binding of the sample and the DNA aptamer; a pharmaceutical composition for preventing metastasis of or treating lung cancer, comprising the DNA aptamer, and a drug delivery system for preventing metastasis of or treating lung cancer, comprising the DNA aptamer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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