Zhengming Chen,Khondaker Islam,Bin Shao,Jiangchao Yao,Donald J. Kyle
申请号：
US12225743
公开号：
US08247442B2
申请日:
2007.03.29
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to azetidinyl, pyrrolidinyl, piperidinyl, and hexahydroazepinyl compounds of Formula I and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein R1-R3 and Z are defined as set forth in the specification. The invention is also directed to the use compounds of Formula I to treat, prevent or ameliorate a disorder responsive to the blockade of calcium channels, and particularly N-type calcium channels. Compounds of the present invention are especially useful for treating pain.
