Akira Matsumura,Hidenori Mikamiyama,Bin Shao,Naoki Tsuno,Jiangchao Yao
申请号：
US12296788
公开号：
US08937181B2
申请日:
2007.04.13
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention relates to azetidinyl, pyrrolidinyl, piperidinyl, and hexahydroazepinyl compounds of Formula (I): and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein R1-R3, Z, p and q are defined as set forth in the specification. The invention is also directed to the use compounds of Formula (I) to treat, prevent or ameliorate a disorder responsive to the blockade of calcium channels, and particularly N-type calcium channels. Compounds of the present invention are especially useful for treating pain.
