The present invention relates to an asymmetrical wheel kit for a manual wheelchair (1), and a wheelchair fitted with the wheel kit to facilitate the practice of a throwing sport activity. The wheel kit is characterized in that it includes two asymmetrical wheels, with a small lateral wheel (10) and a large lateral wheel (42), the small lateral wheel (10) being provided with drive means (24-1, 24-2, 25-1, 25-2, 26, 27, 40, 47 55, 56a, 56b, 54) actuated by a first actuation means (43) arranged on the side of the large lateral wheel (42). This kit can be used in the field of manual wheelchairs for sick or disabled persons.