A medication administration guide having a card member with an elongated opening. A transparent housing with a plurality of pill receiving cells is affixed to the card member in the elongated opening. The guide has a closure flap positioned to enclose the individual cells after a representative pill have been placed in each. The closure flap has one edge permanently affixed to the card member adjacent the elongated opening and a second edge for being selectively affixed to the card member on the opposite side of the elongated opening to enclose the individual cells and contain the pills. Medication information is affixed adjacent to each well has a pill therein on the first side of the card member and contact information is affixed to the second side of the card.