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Process for producing a plasma protein-containing medicament with reduced concentration of citrate and metals
专利权人:
Yendra Linnau;Sonja Svatos;Herwig Igel;Wolfgang Teschner
发明人:
Wolfgang Teschner,Yendra Linnau,Sonja Svatos,Herwig Igel
申请号:
US11151295
公开号:
US08709492B2
申请日:
2005.06.14
申请国别(地区):
US
年份:
2014
代理人:
摘要:
There is disclosed a method of preparing a plasma-protein-containing medicament from citrated plasma or from a citrate-containing plasma fraction, the medicament being substantially free from undesired metals, which method comprises the following steps:exchanging the citrate and optionally citrate-bound metals in a plasma-protein-containing solution for a water-soluble mono- or dicarboxylate or for an organic mono- or dicarboxylic acid under non-precipitating conditions,recovering the plasma protein or the plasma proteins, andfinishing the medicament.
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