Board of Regents of the University of Nebraska;Hospital for Special Surgery
发明人:
申请号：
EP10816063.1
公开号：
EP2475325B1
申请日:
2010.09.09
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
A method of detecting implant loosening in a subject, or determining an increased risk for osteolysis in a subject, said method comprising administering to the subject a composition comprising at least one water soluble polymer and at least one pharmaceutically acceptable carrier, wherein said water soluble polymer is operably linked to at least one imaging agent. A method of inhibiting the loosening of an implant in a subject, or inhibiting osteolysis in a subject, said method comprising administering to the subject a composition comprising at least one water soluble polymer and at least one pharmaceutically acceptable carrier, wherein said water soluble polymer is operably linked to at least one therapeutic agent.
