Andrew R. Miksztal,WeiQi Lin,Mee Jean Kim,Hongwei Wu,Min L. Lee,Wendy Chao
申请号:
US16320074
公开号:
US20200222430A1
申请日:
2017.08.01
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Compositions comprising oxygenated cholesterol sulfates (OCS) are provided. The OCS is, for example, 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or 5-cholesten, 3, 25-diol, disulfate (25HCDS). The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure due to acetaminophen), high cholesterol/high lipids, and various inflammatory diseases and conditions.