The invention pertains to the field of reaction systems generating malodour, particularly from constituents of human sweat. Specifically, the invention pertains to proteins for generating malodours, substrates for generating such malodour, inhibitors of such malodour generation and test and screening systems for measuring their malodour inhibition efficacy and finding substances previously not known to inhibit malodour generation. Thus, the invention also pertains to the field of deodorants.