A compound of formula (I): ** Formula ** or a pharmaceutically acceptable salt, solvate or stereoisomer thereof, wherein: X is C>； = O or CH2； R1 is -Y-R3； R2 is H or (C1-C6) alkyl； Y is: 6 to 10 membered aryl, heteroaryl or heterocycle, each of which may be optionally substituted with one or more halogen； R3 is: - (CH2) n-aryl, -O- (CH2) n-aryl or - (CH2) nO-aryl, wherein the aryl is optionally substituted with one or more: (C1-C6) alkyl, optionally substituted with one or more halogen； (C1-C6) alkoxy, substituted with one or more halogen； oxo； Not me； carboxyl； cyano； hydroxyl； halogen； deuterium； 6 to 10-membered aryl or heteroaryl, optionally substituted with one or more (C1-C6) alkyl, (C1-C6) alkoxy or halogen； -CONH2； or -COO-(C1-C6) alkyl, wherein the alkyl may be optionally substituted with one or more halogen； - (CH2) n-heterocycle, -O- (CH2) n-heterocycle or - (CH2) nO-heterocycle, in which the heterocycle is optionally substituted with one or more: (C1-C6) alkyl, optionally substituted with one or more halogen； (C1-C6) alkoxy, substituted with one or more halogen； oxo； Not me； carboxyl； cyano； hydroxyl； halogen； deuterium； 6 to 10-membered aryl or heteroaryl, optionally substituted with one or more (C1-C6) alkyl, (C1-C6) alkoxy or halogen； -CONH2； or - COO-(C1-C6) alkyl, wherein the alkyl may be optionally substituted with one or more halogen； or - (CH2) n-heteroaryl, -O- (CH2) n-heteroaryl or - (CH2) nO-heteroaryl, wherein the heteroaryl is optionally substituted with one or more: (C1-C6) alkyl, optionally substituted with one or more halogen； (C1-C6) alkoxy, substituted with one or more halogen； oxo； Not me； carboxyl； cyano； hydroxyl； halogen； deuterium； 6 to 10-membered aryl or heteroaryl, optionally substituted with one or more (C1-C6) alkyl, (C1-C6) alkoxy or halogen； -CONH2； or - COO-(C1-C6) alkyl, wherein the alkyl may be optionally substituted with one or more halogen； and n is 0, 1, 2 or 3； wherein the term (C1-C6) alkyl includes (C3-6) cycloal
