YAO, WENQING,姚文清,BURNS, DAVID M.,伯斯 大卫M,伯斯 大衛M,ZHUO, JINCONG,卓金聪,卓金聰,伯斯 大卫M,伯斯 大衛M
申请号:
TW101121953
公开号:
TW201311686A
申请日:
2012.06.19
申请国别(地区):
TW
年份:
2013
代理人:
摘要:
The present invention provides azetidinyl phenyl, pyridyl, or pyrazinyl carboxamide derivatives, as well as their compositions and methods of use, that modulate the activity of Janus kinase (JAKs) and are useful in the treatment of diseases related to the activity of JAK including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.本發明提供吖丁啶基苯基、吡啶基或吡嗪基羧醯胺衍生物,以及其組合物及用法,其調節Janus激酶(JAKs)活性,且適用於治療與JAK活性相關的疾病,包括例如發炎疾病、自體免疫疾病、癌症及其他疾病。