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AN INJECTABLE PREPARATION OF DICLOFENAC SALTS WITH HYDROXYPROPYL- BETA CYCLODEXTRIN AND POLYSORBATE 80
专利权人:
发明人:
DOSHI MANISH UMED,GHOSH ARUNAVA ANIL,MATE SIDDHARTH RAMDAS,MANE GOVIND KONDABARAO
申请号:
IN201727019575
公开号:
IN300571B
申请日:
2015.06.30
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
The present invention relates to injectable preparations containing 75 mg to 100 mg of water soluble salts of diclofenac in about 1ml injection solution, wherein the pH of the solution is maintained at 8-9 using alkali. The composition is suitable for parenteral administration through intramuscular, intravenous, subcutaneous, intradeltoid, intragluteal route of administration. More specifically, the injectable preparations comprise 75 mg/ml of diclofenac sodium in a solvent system containing water and two or more solubilizers along with antioxidants and buffering agents. The invention also provides a method of preparing the injectable preparations. WO2016170401A1
来源网站:
中国工程科技知识中心
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