BOEHRINGER INGELHEIM INTERNATIONAL GMBH;VITAE PHARMACEUTICALS INC
发明人:
RENZ MARTIN,SCHUELE MARTIN,XU ZHENRONG
申请号：
TN2011000484
公开号：
TN2011000484A1
申请日:
2011.09.23
申请国别(地区):
TN
年份:
2013
代理人:
摘要：
This invention relates to novel compounds of the Formula Ik, Im1, Im2, Im5, In1, In2, In5, lo1, lo2, lo5, Ip1, Ip3, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11 BETA-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of Cortisol in a cell or the inhibition of the conversion of cortisone to Cortisol in a cell.
