A method of enhancing the bioavailability of a lipid-soluble nutrient, such asDHA, arachidonic acid, tocopherol, andcarotenoids, in a newborn or preterm infant is disclosed. In this method, thelipid-soluble nutrient is administered in a nutritionalproduct (such as an infant formula) to a preterm or newborn infant Thenutritional product comprises (a) an effective amount of thelipid-soluble nutrient, and (b) a fatty component comprising a combination of:(i) at least 6 g/l predigested fat, wherein thepredigested fat includes at least one of monoglycerides, free fatty acids, ora combination of monoglycerides and free fatty acids, and (ii)at least 1 44 g/l phospholipid A method of enhancing cognition in newborn orpreterm infants utilizing the nutritional product isalso disclosed.