GIUST, WALTER,SOUZA, FABIO,OUDENES, JAN,GORIN, BORIS,BEJAN, ELENA
申请号:
CA2726599
公开号:
CA2726599A1
申请日:
2010.12.30
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Disclosed is a process for preparing a treprostinil salt. The process involvesthestep of dissolving treprostinil in a water-miscible organic solvent to form atreprostinil solution. The treprostinil solution is reacted with an aqueousbasicsolution containing an alkali metal cation to form treprostinil salt. Allowingcrystallization of the treprostinil salt to take place, and then collectingthetreprostinil salt formed.