Direct Dissolution Of Docetaxel In A Solvent In Polysorbate 80

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专利权人:

Aventis Pharma S.A.

发明人:

Authelin, Jean-Rene,Didier, Eric,Fouque, Elie,Nakach, Mostafa

申请号：

AU2012227181

公开号：

AU2012227181A1

申请日:

2012.09.19

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

#$%^&*AU2012227181A120121011.pdf#####Abstract The invention relates to the preparation of a solution of docetaxel in polysorbate 80. The process disclosed by the instant application involves eluting a solution comprising docetaxel, polysorbate 80 and an organic solvent through a purification column. The organic solvent in the solution eluted from the purification column is removed by evaporation under reduced pressure to yield a composition of docetaxel in polysorbate 80.

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