Thomas Harold Mareci,Paul Richard Carney,Garrett William Astary,Hector Sepulveda,Michele Viola Manuel,Charles Robert Fisher
申请号:
US13389289
公开号:
US20120133363A1
申请日:
2010.08.09
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Electrodes, infusion cannula, and interventional MRI instrumentation, are constructed with multiple layers or mixtures of metals or alloys that allow the diamagnetic behavior of some metals to combine with the paramagnetic behavior of others, wherein the devices have a magnetic susceptibility which is close to that of the material, for example body tissue, being im The material may thereby be imaged using MRI with resultant images having greatly reduced distortion. Optimal metal composites are determined through mathematical modeling and measurements. In particular, MR compatible susceptibility-matched electrodes may be used for stimulation and for acquiring electroencephalography (EEG) data before, during and after MR image and spectroscopy measurements, with a significant reduction in distortion of the resulting images and spectra. In accordance with the invention, these electrodes may further be incorporated into micro-electrode arrays. In addition, MR compatible susceptibility-matched cannula can implanted before, during and after MR image and spectroscopy measurements, with a significant reduction in distortion of the resulting images and spectra.