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Branched 3-phenylpropionic acid derivatives and their use
专利权人:
Bayer Intellectual Property GmbH
发明人:
HAHN, Michael,LAMPE, Thomas,STASCH, Johannes-Peter,SCHLEMMER, Karl-Heinz,WUNDER, Frank,LI, Volkhart,BECKER-PELSTER, Eva-Maria,STOLL, Friedericke,KNORR, Andreas,WOLTERING, Elisabeth
申请号:
ES12711861
公开号:
ES2561753T3
申请日:
2012.03.28
申请国别(地区):
ES
年份:
2016
代理人:
摘要:
Compound of the formula (I) ** Formula ** in which R1, R2 and R3 independently from each other represent hydrogen or methyl, L represents a bond or represents -CH2-, R4A and R4B independently from each other represents methyl, trifluoromethyl or ethyl or R4A and R4B are linked together and together with the carbon atom to which they are attached, they form a cyclopropyl or cyclobutyl ring, which can be substituted up to twice with fluorine, R5 represents hydrogen, fluorine, methyl or methoxy, R6 represents hydrogen , fluorine, chlorine, bromine, cyano, methyl, trifluoromethyl, ethyl, methoxy or trifluoromethoxy, R7 represents hydrogen, fluorine, chlorine or methyl, R8A represents methyl or ethyl, R8B represents trifluoromethyl, or R8A and R8B are linked together and together with the carbon atom to which they are attached, form a cyclopentyl ring optionally substituted with difluoro, of the formula ** Formula ** R9 represents fluorine, chlorine, bromine, cyano, (C1-C4) alkyl, (C2-C4) alkenyl, cycloprop ilo or cyclobutyl, with alkyl (C1-C4) and alkenyl (C2-C4) being substituted up to three times with fluorine and cyclopropyl and cyclobutyl up to twice with fluorine, and R10 represents hydrogen, fluorine, chlorine, methyl, trifluoromethyl, ethyl or Methoxy, as well as its salts, solvates and solvates of salts.Compuesto de la fórmula (I)**Fórmula** en la que R1, R2 y R3 independientemente entre sí representan hidrógeno o metilo, L representa un enlace o representa -CH2-, R4A y R4B independientemente entre sí representan metilo, trifluorometilo o etilo o R4A y R4B están enlazados entre sí y junto con el átomo de carbono al que están unidos, forman un anillo ciclopropilo o ciclobutilo, que puede estar sustituido hasta dos veces con flúor, R5 representa hidrógeno, flúor, metilo o metoxi, R6 representa hidrógeno, flúor, cloro, bromo, ciano, metilo, trifluorometilo, etilo, metoxi o trifluorometoxi, R7 representa hidrógeno, flúor, cloro o metilo, R8A representa metilo o etil
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中国工程科技知识中心
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