Christophe Moinet,Charles Blais,Monica Bubenik,Laval Chan Chun Kong,Marc Courchesne,Oswy Z. Pereira,Réal Denis,Louis Vaillancourt,Constantin G. Yannopoulos
申请号：
US12304685
公开号：
US08124613B2
申请日:
2007.06.14
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Compounds according to formula (I):wherein R1, R2, R3, n and X are defined as defined herein, and the pharmaceutically acceptable salts, hydrates and solvates thereof, are useful for the modulation of CCR5 chemokine receptor activity. Additionally, compounds according to Formula III:wherein Z, R′1, and R′2 are defined as defined herein, and the pharmaceutically acceptable salts, hydrates and solvates thereof, are useful as intermediates for production of compounds that modulate CCR5 chemokine receptor activity.
