Eric Marsault,Kamel Benakli,Hamid Hoveyda,Mark L. Peterson,Sylvie Beaubien,Luc Ouellet,Carl St-Louis,Sophie Beauchemin
申请号：
US14873056
公开号：
US10040751B2
申请日:
2015.10.01
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention is directed to novel macrocyclic compounds of formula (I) and their pharmaceutically acceptable salts, hydrates or solvates:wherein R1, R2, R3, R4, R5, R6, n1, m, p Z1, Z2, and Z3 are as described in the specification. The invention also relates to compounds of formula (I) which are antagonists of the motilin receptor and are useful in the treatment of disorders associated with this receptor and with or with motility dysfunction.
