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A medicament for use in a method of inducing or extending a cellular cytotoxic immune response
专利权人:
Bundesrepublik Deutschland Letztvertreten Durch Das Robert Koch-Institut Vertreten Durch Seinen Prasidenten
发明人:
Kroczek, Richard
申请号:
AU2015233542
公开号:
AU2015233542A1
申请日:
2015.03.17
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The present invention relates to a medicament for use in a method of extending a cellular cytotoxic immune response against an antigen-comprising protein, the method comprising the step of: i) administering to a patient having T cells activated against an antigen a peptide-loaded major histocompatibility complex class I (MHC-I) presenting cell and an adjuvant which supports a Th-1-mediated response, wherein the peptide is derived from the antigen-comprising protein, thereby re-activating the activated T cell, wherein the peptide-loaded major histocompatibility complex class I (MHC-I) presenting cell of step i) is administered in a time frame of from 0 h to 14 days after the T cells were activated against an antigen.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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