A defective adenosine vector that includes putting nucleic acid molecules under the control of a CMV driver in the E1 region rather than the E1 region and encoding a mutant polymer that includes a series of amino acids, such as ID:5 or protein. A/As shown in ID No.6 or ID No.8, the aggregation consists of a series of amino acids, in which the adenosine vector includes the following characteristics: it is a human adenosine subspecies that destroys all or part of the E3, and/or E1 Elim regions of the non-basic region. It is replaced by a 5'to 3'expression band.1. CMV direct enhancer/actuator, a beta-GLOBIN/IGG human chemical molecule, a nucleic acid molecule, which can encode a variant polyurethane, including a series of carbamates, as shown in ID No.5, or a fusion protein, including a series of ammonia water. Acids such as SEC ID No.6 or SEC No.8 and SV40 Delayed Polyamide Senal It also refers to an ingredient that can be used to induce an immune response to hepatitis B virus, with the aim of providing protection or treatment for this infectious disease.Referido a un vector adenoviral defectuoso que comprende insertar en lugar de la region E1 una molecula de acido nucleico colocada bajo el control de un promotor de CMV, y que codifica un polipeptido mutante que comprende una secuencia de aminoacidos como se muestra en la SEC ID NO: 5 o una proteina de fusion que comprende una secuencia de aminoacidos como se muestra en la SEC ID NO:6 o la SEC ID NO: 8, en donde dicho vector adenoviral comprende las siguientes caracteristicas: es un subgenero de adenovirus humano Ad5, se elimina toda o parte de la region no esencial E3, y/o la region E1 eliminada se reemplaza por un casete de expresion que contiene, de 5' a 3', el potenciador/promotor temprano inmediato de CMV, un intron beta-globin/IgG humano quimerico, la molecula de acido nucleico que codifica un polipeptido mutante que comprende una secuencia de aminoacidos como se muestra en la SEC ID NO:5 o una proteina de fusio
