The present invention provides a novel pharmaceutical composition based on theuse of a particular oil phase which comprises alipophilic, pharmaceutically active agent, a mixture of diglyceride andmonoglyceride in a ratio of from about 9:1 to about 6:4 by weight(diglyceride:monoglyceride) wherein the diglyceride and monoglyceride are mono-or di-unsaturated fatty acid esters of glycerol havingsixteen to twenty-two carbon chain length, one or more pharmaceuticallyacceptable solvents, and one or more pharmaceutically acceptablesurfactants. The composition is in a form of self-emulsifying formulationwhich provides high concentration and high oral bioavailabilityfor lipophilic compounds.
