Derek Parry Jewell;Adrian Vivian Sinton Hill;Robert Paul Anderson
发明人:
Robert Paul Anderson,Adrian Vivian Sinton Hill,Derek Parry Jewell
申请号：
US11556208
公开号：
US08329144B2
申请日:
2006.11.03
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A peptide analogue which is not more than 50 amino acids in length, and which is capable of being recognized by a T cell receptor that recognizes an epitope comprising sequence 62PQPELPY68 (SEQ ID NO:1), and fusion proteins, pharmaceutical compositions, and kits comprising the same, are provided herewith. Also provided are methods of diagnosing coeliac disease, or susceptibility to coeliac disease, in an individual comprising contacting a sample from the individual with a peptide analogue and determining in vitro whether T cells in the sample recognize the peptide analogue.
