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Methods for Identifying and Treating an Individual with an Inflammatory Disease using Fatty Acid-Based Therapies
专利权人:
发明人:
Floyd H. Chilton
申请号:
US14367158
公开号:
US20150005382A1
申请日:
2012.10.04
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides methods of identifying a subject as responsive to treatment of an inflammatory disease and/or inflammation with one or more polyunsaturated fatty acids (PUFAs), comprising detecting, in a nucleic acid sample of a subject having an inflammatory disease and/or inflammation, the presence of a C allele at single nucleotide polymorphism (SNP) rs730012 in the leukotriene C4 synthase gene, wherein the presence of said C allele at rs730012 in said nucleic acid sample from the subject indicates that the subject is responsive to treatment of said inflammatory disease and/or inflammation with one or more PUFAs.
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