For example as for this invention, after the transplanting to the body organization long-term existence introduction to the region of the showing and soft organization (, the injection, transplantation or the pad through) the muscular origin fore-quarter cell which can make soft organization increase afterwards is offered. Method, and the said cell in order isolation to print the muscular origin fore-quarter cell and, it offers also the method in order to alter be inherited for gene importation remedy. This invention the mammal (includes the person making use of the composition which includes the muscular origin fore-quarter cell various functional states (malformation and the injury, fragile, the disease, or dysfunction it is listed) at the time of dealing with,) to make soft organization increase and method in order to increase capacity furthermore is offered. Especially, this invention offers the disposal and improvement of the urine incontinence and other urine road condition.本発明は、体組織への移植後に長期生存を示しかつ軟組織の部位への導入(例えば、注射、移植もしくは埋め込みを介して)後に軟組織を増大させ得る筋肉由来前駆細胞を提供する。筋肉由来前駆細胞を単離刷るための方法、および該細胞を遺伝子移入治療のために遺伝的に改変するための方法もまた、提供する。本発明は、種々の機能状態(形成異常、傷害、虚弱、疾患、もしくは機能不全が挙げられる)の処置において、筋肉由来前駆細胞を含む組成物を用いて、哺乳動物(ヒトを含む)軟組織を増大させかつ容積を増すための方法をさらに提供する。特に、本発明は、尿失禁および他の尿路病状の処置および改善を提供する。
