Gourab Bhattacharjee,Alexey Revenko,Robert A. MacLeod
申请号:
US14124621
公开号:
US09187749B2
申请日:
2012.06.08
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed herein are methods for decreasing Factor 12 and treating or preventing inflammatory conditions in an individual in need thereof. Examples of disease conditions that can be ameliorated with the administration of antisense compounds targeted to Factor 12 include hereditary angioedema (HAE). Methods for inhibiting Factor 12 can also be used as a prophylactic treatment to prevent individuals at risk for developing an inflammatory condition, such as, hereditary angioedema.