methods for modulating an inflammatory response to ameliorate an inflammatory disease, disorder or condition in an animal, to treat an animal at risk for an inflammatory disease, disorder or condition, to inhibit factor xi expression in an animal, to reduce the risk of an inflammatory disease, disorder or condition, in an animal, to treat an animal at risk for an inflammatory disease, and to treat an animal having an inflammatory disease, and use of a factor xi-labeled compound
Brett P. Monia,Jeffrey R. Crosby,Robert A. Macleod,Susan M. Freier
申请号：
BRPI1015236
公开号：
BRPI1015236A2
申请日:
2010.04.15
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
Disclosed herein are antisense compounds and methods for modulating Factor XI and modulating an inflammatory disease, disorder or condition in an individual in need thereof. Inflammatory diseases in an individual such as arthritis and colitis can be ameliorated or prevented with the administration of antisense compounds targeted to Factor XI.
