SHALWITZ, ROBERT,GARDNER, JOSEPH, H.,JANUSZ, JOHN, M.
申请号：
EP12796395
公开号：
EP2717870A4
申请日:
2012.06.05
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
The invention relates to a composition for use in a method for treating cancer in a subject. The composition comprises the compound {[5-(3-fluorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid or a pharmaceutically acceptable salt thereof. The invention further provides in vitro or ex vivo methods for increasing levels of sVEGF-1 secreted from a cell and for decreasing levels of PGK in a cell comprising administering to the cell an effective amount of {[5-(3-fluorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid. {[5-(3-fluorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid has the formula
