SHALWITZ, ROBERT,GARDNER, JOSEPH H.,JANUSZ, JOHN M.
申请号：
CA2837560
公开号：
CA2837560A1
申请日:
2012.06.05
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
Disclosed herein is {[5-(3-fluorophenyl)-3-hydroxypyridine-2-carbonyl]-amino} acetic acid and the ester and amide prodrugs thereof, that can stabilize hypoxia inducible factor-2 alpha (HIF-2a) and thereby provide a method for treating cancer. Further disclosed are compositions which comprise {[5-(3-fluorophenyl)-3-hydroxypyridine-2-carbonyl]-amino} acetic acid and/or a prodrug thereof which can be used to treat cancer.
