FRAUNHOFER, WOLFGANG,KRAUSE, HANS-JUERGEN,NEU, MICHAEL
申请号:
EP10772644
公开号:
EP2427211A4
申请日:
2010.05.03
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The invention provides a liquid pharmaceutical formulation which does not include NaCl and comprises more than 20 mg of a polyol and at least about 100 mg/mL of a human anti-TNF-alpha antibody, or antigen-binding portion thereof. The invention provides a high concentration antibody formulation having long-term stability and advantageous characteristics for subcutaneous administration.