Fraunhofer, Wolfgang,Krause, Hans-Juergen,Neu, Michael
申请号：
AU2013204238
公开号：
AU2013204238A1
申请日:
2013.04.12
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
#$%^&*AU2013204238A120130509.pdf#####STABLE HIGH PROTEIN CONCENTRATION FORMULATIONS OF HUMAN ANTI-TNF-ALPHA-ANTIBODIES Abstract The invention provides a liquid pharmaceutical formulation which does not include NaCl and comprises more than 20 mg of a polyol and at least about 100 mg/mL of a human anti-TNF-alpha antibody, or antigen-binding portion thereof. The invention provides a high concentration antibody formulation having long-term stability and advantageous characteristics for subcutaneous administration.
