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Tris(hydroxymethyl)aminomethane salts of a small-molecule GLP1R agonist and pharmaceutical compositions and uses thereof
专利权人:
TransTech Pharma; LLC
发明人:
Almariego, Danilo,Polisetti, Dharma Rao,Benjamin, Eric,El Abdellaoui, Hassan,Sahoo, Soumya P.
申请号:
AU2013235167
公开号:
AU2013235167A1
申请日:
2013.03.20
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The disclosure provides tris(hydroxymethyl)aminomethane salts of a small-molecule GLP1 R agonist. The disclosure further provides solid compositions comprising tris(hydroxymethyl)aminomethane salts of the small-molecule GLP1R agonist. The disclosure further provides uses of tris(hydroxymethyl)aminomethane salts of a small-molecule GLP1R agonist, e.g., for treating type 1 diabetes, type 2 diabetes, or obesity. Solid formulations further comprising an evaporation residue and a binder, such as hydroxy propyl methyl cellulose acetate succinate (HPMCAS), are also provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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