ALMARIEGO, DANILO,POLISETTI, DHARMA RAO,BENJAMIN, ERIC,EL ABDELLAOUI, HASSAN,SAHOO, SOUMYA P.
申请号：
CA2868033
公开号：
CA2868033A1
申请日:
2013.03.20
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The disclosure provides tris(hydroxymethyl)aminomethane salts of a small-molecule GLP1 R agonist. The disclosure further provides solid compositions comprising tris(hydroxymethyl)aminomethane salts of the small-molecule GLP1R agonist. The disclosure further provides uses of tris(hydroxymethyl)aminomethane salts of a small-molecule GLP1R agonist, e.g., for treating type 1 diabetes, type 2 diabetes, or obesity. Solid formulations further comprising an evaporation residue and a binder, such as hydroxy propyl methyl cellulose acetate succinate (HPMCAS), are also provided.
